Vascular Disorders of the Liver: VALDIG's Guide to Management and Causes

This book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach. This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.

About the Author

He leads a research group working on the effects of the intestinal immune system on the regulation of blood flow at the Institute of Research in Biomedicine in Bellinzona. As a researcher-clinician, he coordinates a multicentre project on thrombotic disorders of the liver and participates as a co-investigator in several international studies including the European reference Network on Rare Liver Diseases. He serves as chair of the EASL-VALDIG Consortium (vascular liver disease group). Former president of the Swiss Association for the Study of the Liver and co-founder of the Swiss liver patient association.

Pierre-Emmanuel Rautou (MD, PhD) graduated from Bordeaux Medical School in 2003. He completed his residency in Hepatology and Gastroenterology in Assistance PubliqueHôpitaux-de-Paris until 2009 and received his medical degree from the University of ParisVII. He spent 4 years as a research fellow at the INSERM Unit 970 in the laboratory of Drs Alain Tedgui and Chantal Boulanger (Paris Cardiovascular Research Center @HEGP) where he studied the effects of cell derived microparticles on endothelial cells. He earned his Doctoral degree in vascular biology and haemostasis in 2011 from the University of Paris-VII. He then joined the haemostasis laboratory of Prof. Nigel Mackman at University of North Carolina at Chapel Hill (USA) where he studied the role tissue factor in chronic liver diseases. In 2012, Dr Rautou joined the department of Hepatology at the University of Paris-VII (Hôpital Beaujon, Clichy, France) as Assistant Professor to take the lead of the splanchnic hemodynamic laboratory. He is also researcher at the INSERM Unit 970 (Paris Cardiovascular Research Center @HEGP) in a team dedicated to endothelial cell biology. Pierre-Emmanuel Rautou is member of the French Association for the Study of the Liver (AFEF). He serves on the editorial board of the Journal of Hepatology. He became member of the EASL young investigator concerted action group in 2013.