Ion and Molecule Transport in Lysosomes

Lysosomes are key subcellular organelles that regulate the cell function. Many of the essential activities of the cell are dependent on lysosomes. Dysfunction is linked to multiple diseases - storage disorders, neurodegeneration, immunological diseases and cancer. This book discusses concepts and methods used to study lysosome ion and small molecule transport. The contents will not only attract accomplished investigators in need of a broad review and synthesis of this important subject but will also appeal to young investigators and trainees needing to acquire comprehensive knowledge and technical skills working with lysosomal ion channels and small molecule transporters.Key selling features:Summarizes the endocellular role that lysosomes play with respect to cellular waste disposalReviews essential cellular functions of lysosomesExplores how lysosome dysfunction is the cause of many metabolic disordersExamines how lysomes are involved in storage diseasesDescribes various technologies and methods used in lysosome research

About the Author

Bruno Gasnier is CNRS Research Director, Group Leader at CNRS/Paris Descartes. Michael Xi Zhu is currently with the Department of Integrative Biology and Pharmacology at the University of Texas Health Science Center at Houston.